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Diagnostic Criteria for Systemic Lupus Erythematosus - ACR and SLICC Criteria

#Diagnosis #Rheumatology #SLE #Lupus #Erythematosus #Criteria
Diagnostic Criteria ... ACR and SLICC Criteria ... #Diagnosis #Rheumatology ... #SLE #Lupus #Erythematosus ... #Criteria #ACR
Lupus is diagnosed using clinical and laboratory diagnostic criteria set by the American College of Rheumatology.
Lupus is diagnosed ... using clinical ... A diagnosis of lupus ... #SLE #Lupus #Erythematosus ... #Criteria #ACR
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... SLE) Clinical ... (for secondary APS ... #rheumatology # ... #management #treatment
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
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Systemic Lupus Erythematosus ... Anti-cardiolipin (aPL ... - Anti-B2GP1 (aPL ... Lupusreference #SLE ... #Erythematosus
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Clinical Domains ... pericarditis • Hematologic ... Classification #Criteria #SLE ... #diagnosis #rheumatology
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid antibodies (aPL ... ): • Lupus anticoagulant ... Anticardiolipin antibodies (aCL ... of 1 clinical event ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... #Diagnosis #Management ... #Summary #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ... , others (RNP, aPL ... Anti-cardiolipin (aCl ... glycoprotein I (ß2GP), Lupus ... #diagnosis #associations
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... thiazidic, PPI, ACE ... Erythematosus ( ... #sle #comparison ... #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... ACLE) • Erythematous ... Differential Diagnosis ... #Diagnosis #Rheumatology