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rheumatology syndrome erythematosus systemic criteria druginduced hepatology neurology table activation aih anticoagulation antiphospholipid apml arthritis associations autoantibodies autoimmune cardiology cardiomyopathy
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid antibodies (aPL ... ): • Lupus anticoagulant ... Anticardiolipin antibodies (aCL ... to be present Treatment ... #diagnosis #management
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... , others (RNP, aPL ... Anti-cardiolipin (aCl ... glycoprotein I (ß2GP), Lupus ... #diagnosis #associations
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... (for secondary APS ... Erythematosus #SLE ... #management #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... thiazidic, PPI, ACE ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Lupus is diagnosed using clinical and laboratory diagnostic criteria set by the American College of Rheumatology.
Lupus is diagnosed ... using clinical ... A diagnosis of lupus ... #SLE #Lupus #Erythematosus ... #Criteria #ACR
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... Erythematosus #Diagnosis ... #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Erythematosus Clinical ... pericarditis • Hematologic ... Classification #Criteria #SLE ... Erythematosus #diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: - Neuro: AMS ... have fever - ACS ... organ damage • Treatment ... Syndrome #TLS #diagnosis ... #management #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
and Management ... shunt (Type 2) Clinical ... Treatment: • ... #management #treatment ... #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... 5 or elevated Cr ... Renal Failure Treatment ... #management #hematology
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