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diagnosis management differential algorithm hematology guidelines acr2021 lupus classification sle systemic table erythematosus oncology syndrome syndromes autoantibodies causes cryoglobulinemia diseases
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
scleroderma) - Anti-Scl ... Vasculitis: • ... Renal-limited vasculitis ... antibodies #diagnosis #rheumatology ... #diseases
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
ANCA-Associated ... Vasculitis A group ... , small-vessel vasculitis ... PR3 Anti-GBM disease ... PR3 #Diagnosis #Rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... Anti-cardiolipin (aCl ... Polymerase Ill • ANCA ... Vasculitis: P-ANCA ... Autoantibodies #Rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
syndrome Anti-Scl ... c-ANCA - Vasculitis ... granulomatosis p-ANCA ... - Vasculitis, e.g ... diagnosis #table #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis: + MPO-ANCA ... (Granulomatous disease ... atherosclerotic disease ... most important diseases ... differential #diagnosis #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of Vasculitis ... Vasculitis of ... small vessels - ANCA-associated ... vasculitis ... Vessels #Diagnosis #Rheumatology
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (MPA) - ANCA ... Vasculitis Management ... Algorithm - ACR ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Active
Polyangiitis (EGPA) - ANCA ... Vasculitis Management ... Algorithm - ACR ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
involvement: Anti-GBM Disease ... (C-ANCA): GPA > ... (P-ANCA): eGPA, ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm #rheumatology
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
Vasculitis - Break ... by large vessel vasculitis ... concept is that all ... basement membrane; ANCA ... #Diagnosis #Rheumatology
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