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diagnosis management differential sle algorithm erythematosus systemic acr2021 autoantibodies classification guidelines table antibodies associations diseases druginduced granulomatosis polyangiitis summary ana
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... glycoprotein I (ß2GP), Lupus ... Vasculitis: P-ANCA ... Autoantibodies #Rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... scleroderma) - Anti-Scl ... Vasculitis: • ... Renal-limited vasculitis ... antibodies #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... Vasculitis: + MPO-ANCA ... (Granulomatous disease ... such as systemic lupus ... differential #diagnosis #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of Vasculitis ... Vasculitis of ... small vessels - ANCA-associated ... - systemic lupus ... Vessels #Diagnosis #Rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
syndrome Anti-Scl ... c-ANCA - Vasculitis ... granulomatosis p-ANCA ... - Vasculitis, e.g ... diagnosis #table #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... involvement: Anti-GBM Disease ... (C-ANCA): GPA > ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... Nodosa (PAN), ANCA ... associated vasculitis ... (RA), Systemic lupus ... Differential #Diagnosis #rheumatology
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (MPA) - ANCA ... Vasculitis Management ... Algorithm - ACR ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Active
Polyangiitis (EGPA) - ANCA ... Vasculitis Management ... Algorithm - ACR ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
thiazidic, PPI, ACE ... constitutional symptoms • Treatment ... life-threatening • Treatment ... Evolution: Chronic disease ... comparison #table #rheumatology
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