26 results
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... Walid Malki, MD, MS ... wandering_er #Tumor #Lysis ... #Syndrome #TLS ... #oncology #management
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... - Workup and Management ... #TLS #Tumor #Lysis ... #Syndrome #diagnosis ... #management #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor Lysis ... Syndrome Leukostasis ... have fever - ACS ... #diagnosis #management ... #hematology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor Lysis ... Syndrome (TLS) ... #TumorLysis #Syndrome ... TLS #diagnosis #management ... #oncology
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... Burkitt, SCLC Cells all ... above #Tumor #Lysis ... #Syndrome #TLS ... Pathophysiology #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Diagnosis and Management ... Myelodysplastic #Syndrome ... #treatment #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... & DIC • Tumor lysis ... syndrome: Develops ... #Leukemia #Hematology ... #Oncology #Diagnosis
Outpatient Hypertension Management Algorithm
Monotherapy: 
 • Thiazide/thiazide-like 
 • ACE-I (non-black patients), 
 • ARB
Outpatient Hypertension Management ... Combined: • ACE-I ... Acute Coronary Syndrome ... Amy Chung, MD, MSc ... #Hypertension #Management
Evaluation of Electrical Injury in the Emergency Department 

Common Injuries by System:

CNS - Seizure, coma, spinal
ED arrival MSK ... posterior shoulder - AC ... compartment syndrome ... especially with AC ... Evaluation #Diagnosis #Management
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Features: POEMS, AL ... capillary leak syndrome ... • Schnitzler syndrome ... Differential #Diagnosis #hematology ... #oncology