22 results
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... purpura/hemolytic ... uremic syndrome ... , Hematology 2012 ... , p 193 #Diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... coagulation (DIC) - HELLP ... microangiopathy: Thrombotic thrombocytopenic ... #hematology #anemia
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... syndrome (ST-HUS ... anemia" • HELLP ... APLS BCM IM Residency ... #hematology #hemolysis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Framework Non-blanchable ... DIC/TTP/HUS - Hemolytic ... #hematology #rheumatology ... #nonpalpable #dermatology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... Framework Decreased ... antiphospholipid syndrome ... - Pregnancy: HELLP ... #Framework #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... (Hemolysis, Elevated ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Non-lmmune: • HELLP ... Syndrome • TTP ... #Hematology
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
- Differential Diagnosis ... Framework Cardiovascular ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... #differential #diagnosis
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Pregnancy Three syndromes ... (Hemolysis, Elevated ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Schistocytes, thrombocytopenia ... - DIC, TTP, HELLP ... #Algorithm #workup ... #hematology #testing