3063 results
Thiazide induced Hyponatremia - Pathophysiology
 • Reduced distal delivery
 • Inhibition of the NCC (dilution capcity)-
Hyponatremia - Pathophysiology ... permeability increased - ADH ... independent / ADH ... #Hyponatremia #Pathophysiology ... #diagnosis #differential
Diabetes Insipidus vs Syndrome of Inappropriate ADH (SIADH) - Comparison Table

Diabetes Insipidus - Inadequate ADH
SIADH -
Inappropriate ADH ... Insipidus - Inadequate ADH ... SIADH - Excess ADH ... Comparison #Table #Pathophysiology
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... antagonists 6) ADH ... Adenosine #Nephron #Pathophysiology
Hyponatremia Algorithm - ADH Dependent vs Independent
#Diagnosis #Nephro #Hyponatremia #ADHIndependent #Differential #Algorithm
Hyponatremia Algorithm - ADH ... ADHIndependent #Differential
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Hyponatremia - Differential ... Inappropriate ADH ... physiologic stimulus to ADH ... 100 mmol/kg - ADH ... Hyponatremia #Nephrology #Differential
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Hyponatremia - Differential ... Inappropriate ADH ... physiologic stimulus to ADH ... 100 mmol/kg - ADH ... Hyponatremia #Nephrology #Differential
Hyponatremia - Differential Diagnosis Algorithm
ADH Independent:
 • Tea and Toast Syndrome, Beer Potomania - Low solute
Hyponatremia - Differential ... Diagnosis Algorithm ADH ... ADH Dependent: ... #Hyponatremia #Differential
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Wasting vs SIADH - Pathophysiology ... Hypovolaemia → ADH ... SaltWasting #SIADH #Pathophysiology
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
Hyponatremia - Differential ... Inappropriate ADH ... insufficiency ADH ... #Hyponatremia #Differential
Urine Specific Gravity - Interpretation
Specific Gravity = Density of urine / Density of water
SG close to
resistance to ADH ... inappropriate ADH ... Interpretation #diagnosis #differential