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diagnosis hematology causes hemolysis intravascular microangiopathy ttp algorithm arterial bruising coagulation comparison dermatology dic disseminated embolism evaluation extravascular hemolytic hemolyticuremicsyndrome
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table • Thrombotic Thrombocytopenic Purpura (TTP)
Thrombocytopenic ... Purpura (TTP) ... TMA - Drug-induced ... Microangiopathy #TMA #hematology ... #differential #
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
TTP/HUS indicates ... thrombotic thrombocytopenic ... purpura/hemolytic ... , Hematology 2012 ... #Diagnosis #Differential
Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... Often hard to differentiate ... #purpura #TTP # ... #thrombocytopenia ... Diagnosis #Table #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Causes: - Drug induced ... - Hemolytic anemia ... : • DIC, TTP/HUS ... #Differential #
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... hemolysis: • Thrombotic ... ) - Drug-induced ... macroangiopathic hemolytic anemia ... #diagnosis #hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Platelet count reduced ... syndrome - Thrombotic ... - Fanconi anaemia ... - Drug-induced ... pediatrics #diagnosis #differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
thrombocytopenic ... purpura (TTP), ... uremic syndrome (HUS ... Extravascular #Causes #differential ... #anemia
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Petechiae • Purpura ... Hemorrhagic bullae • Purpura ... DDX: • TMA’s (HUS ... - MAHA: TTP/HUS ... treatment #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential ... Hyperhomocysteinemia - Heparin-induced ... thrombocytopenia ... other causes of purpura ... #differential #
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Evaluation for Thrombotic ... Thrombocytopenic ... Purpura Activity ... result in severe anemia ... WBC count and differential
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