6182 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Injury • AST/ALT ... elevation > Alk ... phos • ALT more ... • R value = (ALT ... Transaminitis #diagnosis
HAS-BLED Score - Risk of Major Bleeding in 1 Year
Characteristics (1 point each)
 • Hypertension: Baseline
2x ULN, or AST/ALT ... /Alk phos > 3x ULN ... anticoagulation #diagnosis
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
- Differential Diagnosis ... Hyperparathyroidism, TKI, ALK ... #Differential #Diagnosis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
R-value: Serum (ALT ... /ULN ALT) / (Alk ... phos/ULN ALP) ... • AST/ALT > ALP ... liver #chemistry #diagnosis
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
Negative for EBER, ALK ... hemepath #pathology #diagnosis
Diagnostic Algorithm for Non–Small-Cell Lung Cancer (NSCLC). The upper portion of the algorithm shows the morphologic
Diagnostic Algorithm ... mutations and ALK ... #Diagnosis #Honc
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
kidney, brain ALT ... for the liver ALP ... Transaminase, ALP ... / ULN ALT) / (ALP ... Transaminitis #diagnosis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
- Differential Diagnosis ... or AST > ALP): ... • Severe - ALT ... > ALT or AST): ... Transaminitis #Algorithm #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... to liver than ALT ... • ALT: Specific ... • AST/ALT > ALP ... #differential #diagnosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... Algorithm Severe ALT ... HELLP Moderate ALT ... • Others Mild ALT ... #Differential #Diagnosis