52 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Anti-cardiolipin (aCl ... Anti-centromere, Scl ... #Rheumatology #diagnosis ... #associations # ... table
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
their Disease Associations ... syndrome Anti-Scl ... Autoantibodies #Associations ... #diseases #diagnosis ... #table #rheumatology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
LungDisease #CTILD #Diagnosis ... Differential #Comparison #Table ... #Rheumatology #Associations
Thalassemia - Electrophoresis - Comparison Table
In this disorder it is the defective production of hemoglobin that
Electrophoresis - Comparison Table ... Hemoglobin E - MCV ... Beta #Comparison #Table ... Electrophoresis #Diagnosis
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
syndrome - Na-K-2Cl ... barrtin (recruits Cl ... Thiazide-sensitive Na—Cl ... Kidney #Nephrology #Diagnosis ... #Differential #Table
Effects of Strokes by Location - Anterior vs Posterior Localization

Anterior Circulation 
 - MCA 
 -
Circulation - MCA ... Effects #Neurology #Diagnosis ... #Table #Territories
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Laboratory #Metabolism #ASTALT ... #AlkPhos #Bilirubin ... Pathophysiology #Diagnosis
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Anti-dsDNA 60-80% Association ... Controversial association ... Negative association ... erythematosus #diagnosis ... #rheumatology #table
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation
Kaposi sarcoma (KS):
 • Target organs: Ubiquitous (cutaneous and mucosal
endothelium • Association ... Castleman Disease (MCD ... pre-GC B cells • Association ... differentiated B cells • Association ... diseases #comparison #diagnosis
Differentiating type-I vs. type-II MI

Sorting this out is difficult, often relying heavily on clinical judgement.

A key
give someone 500 mcg ... troponin of 0.7 ng/ml ... The table below ... #Diagnosis #Myocardial ... NSTEMI #Comparison #Table