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diagnosis clinical management radiology cardiology differential pocus algorithm msk video physicalexam xray pharmacology treatment ultrasound anatomy pulmonary comparison cxr hematology
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytic leukemia (APL ... In addition to APL ... myeloid leukemia (AML ... ) t(8;21), AML with ... Rods #AuerRods #APL
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 Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
I see all of these ... promyelocytic #leukemia #APL ... #APML #Pathology
Auer Rods - Bone marrow aspiration revealed 5% blasts and 65% promyelocytes; many promyelocytes had prominent
Clinical #Path #APL
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
) APS is a rare ... Antiphospholipid antibodies (aPL ... antibodies (aß2-GPl ... 1 of the three aPLs ... diagnosed with APS
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Anti-cardiolipin (aPL ... - Anti-B2GP1 (aPL
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
, others (RNP, aPL ... Anti-cardiolipin (aCl
Low-dose aspirin and low-molecular-weight heparin in lupus and Antiphospholipid Syndrome (APS) pregnancy • No previous history of
Antiphospholipid Syndrome (APS ... BUT high-risk aPL ... history thrombotic APS ... history of obstetric APS ... non-criteria" obstetric APS
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
differentiation syndrome in APL
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Incidence: common in APL ... unless severe APLS ... Differentiation #Syndrome #APML
Pregnancy Management in Patients with SLE and/or APS - Conception to Delivery • Stop Teratogenic Drugs
with SLE and/or APS ... echocardiography • aPL ... +/APS - +heparin ... Management #SLE #APS
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