13 results
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events
and CKD. ... and CKD. ... in HFrEF on GDMT ... outcomes in HFrEF on GDMT ... visualabstract #table
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy - Initiation Strategies

 •
Approach: ACE, ARB, ARNI ... -2 Inhibitor → ARNI ... Heart #Failure #CHF ... Guideline #management #GDMT
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy
 • Beta-blocker
 • ACE,
• ACE, ARB, ARNI ... Heart #Failure #CHF ... Guideline #management #GDMT
HFrEF: Guideline Directed Medical Therapy

"Must Be On"
 • ACEI, ARB, or ARNI AND select Beta Blockers
ACEI, ARB, or ARNI ... ACEI or ARB • ARNI ... #medications #chf ... #cardiology #GDMT
Guidelines Directed medical therapy for Heart Failure 

Satyendra Dhar, MD, @DharSaty

#HFrEF #GDMT #sodium-glucosecotransporter-2inhibitors #SGLT2i #reninangiotensinaldosteronesysteminhibitors
DharSaty #HFrEF #GDMT ... angiotensinreceptorblockers #ARB #ARNI ... #PARADIGM-HF #EMPEROR-Reduced
Guideline-Directed Medical Therapy (GDMT) in HFrEF and CKD

 • Class I pillars of HFrEF GDMT across
Medical Therapy (GDMT ... ) in HFrEF and CKD ... pillars of HFrEF GDMT ... disease: ACEI, ARB, ARNI ... #CKD #HFrEF #management
Stages in the development of HF and recommended therapy by stage. ACEI indicates angiotensin-converting enzyme inhibitor;
development of HF ... angiotensin-receptor blocker; CAD ... ejection fraction; GDMT ... medical therapy; HF ... #CHF #Congestive
Characteristics of Common Lipid Disorders
Polygenic hypercholesterolemia
Atherogenic dyslipidemia
 • Frequently accompanied by central obesity or diabetes
Familial hypercholesterolemia,
history of premature CHD ... individuals exhibit CHD ... Family history of CHD ... Family history, CHD ... diseases #comparison #table
Beta Blockers - Pharmacology Comparison Table
Metoprolol:
 • Receptors: β1
 • Indications: Rate control of a-fib/a-flutter, Suppression
Pharmacology Comparison Table ... indicated in pt w/o CAD ... /HF but limited ... • Indications: Stable ... Pharmacology #Comparison #Table
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
factors: Age>60, CKD ... , CHF, high rate ... diagnosis #comparison #table