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rheumatology erythematosus lupus systemic symptoms cardiology joint myopathy pain vasculitis algorithm autoantibodies autoimmune causes chronic classification comparison conditions extrarticular fuo
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Subacute bacterial endocarditis ... system • Mitral ... - Bacterial endocarditis ... #joint #pain #differential ... #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
) General: Fever ... Photosensitivity, Butterfly rash ... of hip (rare), Arthritis ... erythematosus #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Erythematosus (SLE ... Symptoms Alopecia, Fever ... , Arthralgia / arthritis ... , Myositis Dr ... #diagnosis #rheumatology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm Neoplasm: • NHL • Hodgkin's lymphoma • Leukemia • Solid
Origin (FUO) - Differential ... Diagnosis Algorithm ... Autoimmune: • SLE ... • Giant cell arteritis ... • Infectious endocarditis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... 69% - Malar rash ... 40% - Fever 36% ... anemia 4% - Myositis ... autoantibodies #signs
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... Juvenile idiopathic arthritis ... • Rheumatoid arthritis ... Brucellosis Faget's Sign ... #Patterns #Differential
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
muscle weakness, rash ... proximal joints, Fever ... with temporal arteritis ... Myopathies #myopathy #differential ... #diagnosis #comparison
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... • Rheumatic fever ... • Bacterial endocarditis ... #Diagnosis #MSK
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... • Libman-Sacks endocarditis ... , Fever, Serositis
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Involves aortic and mitral ... • Autoimmune (SLE ... night sweats, fever ... Marantic (NTBE) Differential ... Persistent bacteremia/fevers
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