15 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... : Fever (50%), Depression ... Photosensitivity, Butterfly rash ... lesions Abdominal pain ... #SLE #systemic
Primary and Secondary Causes of Mitral Regurgitation
Primary (organic) chronic mitral regurgitation:
 • Leaflet: Rheumatic fever, Infective
and Secondary Causes ... cushion defects), Systemic ... inflammation (SLE ... Regurgitation #differential ... #diagnosis #cardiology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... ; sometimes « viral ... 9) Unexplained fever ... #diagnosis #sle ... #clues #system
Infectious Joint Pain - Differential Diagnosis Algorithm 
Polyarticular Join Pain
 • Viral Myalgia
 • Viral Arthritis
Infectious Joint Pain ... - Differential ... Infection • Endocarditis ... Infectious #JointPain #MSK ... #Orthopedics #Causes
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Subacute bacterial endocarditis ... • Mitral regurgitation ... - Bacterial endocarditis ... #differential # ... diagnosis #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Rash - Differential ... Red Flags: • Fever ... lesions • Severe pain ... Schonlein Purpura - Endocarditis ... Autoimmune Vasculitis (lupus
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
Inflammatory Joint Pain ... Arthritis • Systemic ... Lupus Erythematosus ... Inflammatory #JointPain #MSK ... #Orthopedics #Causes
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Arthritis: • Joint pain ... • Libman-Sacks endocarditis ... #Systemic #Lupus
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Involves aortic and mitral ... • Autoimmune (SLE ... night sweats, fever ... Vascular: • Systemic ... Marantic (NTBE) Differential
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential ... pain/Night sweats ... Infection - Systemic ... arthritis - SLE ... diagnosis #msk #