15 results
Primary and Secondary Causes of Mitral Regurgitation
Primary (organic) chronic mitral regurgitation:
 • Leaflet: Rheumatic fever, Infective
Leaflet: Rheumatic fever ... , Infective endocarditis ... , Infective endocarditis ... cardiomyopathy - VA Joint ... Regurgitation #differential
Infectious Joint Pain - Differential Diagnosis Algorithm 
Polyarticular Join Pain
 • Viral Myalgia
 • Viral Arthritis
Infectious Joint ... Pain - Differential ... Polyarticular Join ... & Symmetrical Rash ... Infection • Endocarditis
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
muscle weakness, rash ... , Fever, No muscle ... Detectable HIV viral ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... (SLE) General: Fever ... Photosensitivity, Butterfly rash ... phenomenon (20%) Joints ... Pericarditis, Endocarditis
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint ... acute rheumatic fever ... spondyloarthropathies, lupus ... • Acute = Viral ... approach #workup #differential
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Pain Rash ... • Rheumatic fever ... lesions • Discoid lupus ... #skin #rashes #differential
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential ... Red Flags: • Fever ... Schonlein Purpura - Endocarditis ... Autoimmune Vasculitis (lupus ... #Differential #
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Subacute bacterial endocarditis ... Cardiovascular system • Mitral ... - Bacterial endocarditis ... #pain #differential
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... everywhere) 2) A rash ... the face (many differential ... ; sometimes « viral ... 9) Unexplained fever
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... Arthritis: • Joint ... • Libman-Sacks endocarditis ... to: Arthritis, Fever