18 results
Primary and Secondary Causes of Mitral Regurgitation
Primary (organic) chronic mitral regurgitation:
 • Leaflet: Rheumatic fever, Infective
Leaflet: Rheumatic fever ... • Prosthetic valve ... annulus valve: ... cardiomyopathy - VA Joint ... #differential #diagnosis
Systolic Murmurs - Differential Diagnosis Algorithm
Benign / Flow / Hyperdynamic:
 • Pregnancy
 • Fever
 • Anemia
Supravalvular
Systolic Murmurs - Differential ... Diagnosis Algorithm ... • Trauma Mitral ... Murmurs #Cardiology #Differential ... #Diagnosis #Algorithm
Relative Risk of Various Predisoosing Conditions for Infective Endocarditis 
High Risk:
 - Prosthetic valves 
 -
- Aortic valve ... disease - Mitral ... regurgitation ... RiskFactors #Cardiology #Diagnosis ... #Differential #
Causes of Severe Aortic Regurgitation - Differential Diagnosis
Acute:
 • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
- Differential ... Diagnosis Acute ... Acute Prosthetic Valve ... , Rheumatic Fever ... Inflammatory: Lupus
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Subacute bacterial endocarditis ... Cardiovascular system • Mitral ... regurgitation and ... #pain #differential ... #diagnosis #rheumatology
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Involves aortic and mitral ... regurgitation ... night sweats, fever ... Marantic (NTBE) Differential ... #Endocarditis #diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... (SLE) General: Fever ... Pericarditis, Endocarditis ... , Aortic valve lesions ... signs #symptoms #diagnosis
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
, Fever, No muscle ... Detectable HIV viral ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential ... #diagnosis #comparison
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... acute rheumatic fever ... spondyloarthropathies, lupus ... • Acute = Viral ... approach #workup #differential
Endocarditis checklist
Initial evaluation
 • Peripheral blood cultures (three sets at three different sites)
 • Additional culture
(e.g., spine, joints ... consultation • Valve ... regurgitation or ... • Persistent fever ... #criticalcare #diagnosis