23 results
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Algorithm for Differentiating ... Gitelman syndrome ... Chloride • Urine Ca ... #nephrology #hypokalemia ... #diagnosis
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
in the distal tubule ... H+ secretion → Hypokalemia ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology ... #diagnosis
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
Hyponatremia Diagnosis ... Algorithm UOsm ... EABV) - Consider: Hypovolemia ... #algorithm #causes ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... Bartter syndrome, Gitelman ... #Algorithm #causes ... potassium #low #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Algorithm Syndrome ... Malignancy True hypovolemia ... #Nephrology #Differential ... #Diagnosis #Algorithm
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Algorithm Syndrome ... Malignancy True hypovolemia ... #Nephrology #Differential ... #Diagnosis #Algorithm
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia ... Algorithm Hypertonic ... ON (UNa < 30): Hypovolemia ... #Algorithm #diagnosis ... #sodium #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... - Differential Diagnosis ... Algorithm Hypovolemia ... #Algorithm #Causes ... #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
- Differential Diagnosis ... Algorithm Defining ... Bartter's syndrome, Gitelman's ... #algorithm #causes ... #nephrology #potassium
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Diagnosis Algorithm ... Bartter's syndrome, Gitelman's ... syndrome #Hypokalemia ... #Algorithm #nephrology