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differential causes nephrology algorithm potassium medications emesis high management treatment vomiting acidosis aniongap diuresis diuretics druginduced drugs dysgeusia endocrinology excretion
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Hyperkalemia ... Angiotensin-converting enzyme (ACE ... #differential #diagnosis ... pathophysiology #pharmacology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... • NSAIDs • ACE ... (Uncontrolled diabetes ... paralysis - Insulin ... #differential #diagnosis
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
- Differential Diagnosis ... Hyperparathyroidism • Diabetic ... Sarcoidosis • Hypercalcemia ... - Drug-Induced ... drugs • ACE
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... • NSAIDs • ACE ... (Uncontrolled diabetes ... paralysis - Insulin ... #differential #diagnosis
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Ketoacidosis: Diabetic ... Hypokalemia ... Drug-induced hyperkalemia ... ACE-Is and ARBs ... #differential #diagnosis
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Medications: K+, ACEi ... transfusions), ↓insulin ... Treatments: • Insulin ... vasopressor or HyperK-induced
Pediatric Vomiting - Gastrointestinal and Systemic Causes - Differential Diagnosis Algorithm Hepatobiliary: • Acute Hepatitis • Acute
- Differential Diagnosis ... Pregnancy • Diabetes ... • Uremia • Hypercalcemia ... Labrynthitis Psychiatric ... : • Self-Induced
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... - Differential Diagnosis ... Aldosterone • ACEi ... Aldosterone • Diabetic ... #Differential #Diagnosis
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Increased plasma insulin ... (treatment of diabetic ... (accidental or induced ... #differential #diagnosis
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome • Diagnosis ... Hyponatremia • Hypercalcemia ... syndrome • Lithium-induced ... nephrogenic diabetes ... Diuresis #Nephrology #Pharmacology
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