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Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
UOP/weights - Urine ... rhabdo/TLS) Causes ... Liano 1996) - ATN ... CKD— 13% (mostly ATN ... Nephrology #Diagnosis #Algorithm
Causes of Acute Kidney Injury - Differential Diagnosis Framework 
Pre-Renal
Post-Renal
Intrinsic Renal:
 • Tubules (ATN)
 • Glomerular:
Causes of Acute ... (ATN) • Glomerular ... drtonydang @CMC_IM #AKI ... #KidneyInjury #Causes ... Differential #Diagnosis #Algorithm
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI ... Workup Algorithm ... osmolarity If cause ... #Workup #Algorithm ... Diagnosis #nephrology #causes
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... C3/C4, Other • ATN ... Medicine @SCVMCMed #AKI ... Diagnosis #nephrology #causes ... #algorithm
Causes of Generalized Edema - Differential Diagnosis Algorithm
Overfill (Increased renal sodium retention, Urine Na > 40meq/L)
Causes of Generalized ... Overfill (Increased renal ... sodium retention, Urine ... • NSAlDs • AKI ... #Causes
Urinary Casts in the setting of renal disease
#Clinical #Nephro #Urine #Microscopy #Casts #Comparison #Chart #ATN #AIN
Urinary Casts in ... the setting of renal ... Clinical #Nephro #Urine ... #Microscopy #Casts ... Comparison #Chart #ATN
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... GI losses • Renal ... • Reduced GFR, AKI ... Hypo-osmolar urine ... #Causes
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... GI losses • Renal ... • Reduced GFR, AKI ... Hypo-osmolar urine ... #Causes
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Kidney Injury (AKI ... PROBLEM ~80% of AKI ... IMPROVEMENT If the urine ... CONSIDER INTRINSIC CAUSES ... etiologies due to ATN
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Kidney Injury (AKI ... gammopathy of renal ... malignancies Treatment ... Cisplatin • ATN ... Kidney #Injury #AKI