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Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
Guide to Acute Kidney ... - Urinalysis/microscopy ... UOP/weights - Urine ... Liano 1996) - ATN ... CKD— 13% (mostly ATN
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
sediment Microscopic ... : • Flank pain ... Diagnostic of GN or vasculitis ... Causes of Hematuria ... microscopic and
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... (AKI) - Differential ... Emboli, Thrombosis, Vasculitis ... C3/C4, Other • ATN ... Diagnosis #nephrology #causes
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... microscopy / urinary ... osmolarity If cause ... Glomerulonephritis / Vasculits ... imaging #Acute #Kidney
Causes of Acute Kidney Injury - Differential Diagnosis Framework 
Pre-Renal
Post-Renal
Intrinsic Renal:
 • Tubules (ATN)
 • Glomerular:
Causes of Acute ... Kidney Injury - ... (ATN) • Glomerular ... Interstitium (AIN ... drtonydang @CMC_IM #AKI
Urinary Casts in the setting of renal disease
#Clinical #Nephro #Urine #Microscopy #Casts #Comparison #Chart #ATN #AIN
Urinary Casts in ... the setting of renal ... Clinical #Nephro #Urine ... #Microscopy #Casts ... Comparison #Chart #ATN
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Approach to Acute Kidney ... Injury (AKI) 1 ... IMPROVEMENT If the urine ... Assess UA w/ microscopy ... etiologies due to ATN
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... (AKI) in Patients ... gammopathy of renal ... malignancies Treatment ... Cisplatin • ATN
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Diagnostic Criteria HRS-AKI ... (>500mg/d), No haematuria ... , Normal renal ultrasound ... - No other cause ... - No other cause
Urinalysis & Urine Sodium 
Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
Microscopic exam ... Acute Kidney Injury ... (AKI) FE Na < ... Tubular Necrosis (ATN ... #hematuria