52 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... , Drug-induced Lupus ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... pleurisy (search ANA ... person (search ANA ... cytopenia (search ANA ... erythematosus #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies (ANA ... ) ANA or Anti-NucIear ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Auto-Antibodies: - ANA ... (aPL) 30-45% Differential ... Diagnosis and Lupus ... autoantibodies #signs ... #rheumatology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... Diagnosis for Pulmonary ... Complex: Systemic lupus ... , anti-GBM ab, ANA ... , anti-CCP • CXR
Diffuse consolidation
The most common cause of diffuse consolidation is pulmonary edema due to heart failure.
This is
The most common cause ... from the various causes ... Look for other signs ... #Diagnosis #Radiology ... #Pulmonary #CXR
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Workup: - ANA ... Positive in 60-80% of cases ... Erythematosus #Diagnosis ... Management #Summary #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... With associated pulmonary ... #diagnosis #algorithm ... #rheumatology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm ... ASA) • Renal Disease ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... function test, ANA ... #Diagnosis #Causes ... #Workup #hematology