22 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... - Differential Diagnosis ... LFTs #Elevated #Abnormal ... Transaminitis #Algorithm #diagnosis ... #hepatology #LiverFunctionTests
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
of Pregnancy (AFLP ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Hemolysis, Elevated Liver ... exchange 2) Fatty liver ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... • Drugs • AIH ... disease US — Normal ... Others #LFTs #Hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
of Pregnancy (AFLP ... Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... #differential #diagnosis ... #icp #HELLP #AFLP
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Autoimmune: Warm AIHA ... Defects, Drugs, Liver ... Blood Smear ↑ abnormal ... #hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
bleeding disorder Clinical ... bruising • Skin ... PT/INR • Normal ... VonWillebrand #Disease #Diagnosis ... #Hematology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
hypertension 1 A Abnormal ... >2.3mg/dL) 1 Liver ... CHADS2VASc #HASBLED #Comparison ... Anticoagulation #AFib #Diagnosis ... #Hematology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... Areas of diagnostic ... ALP, alkaline phosphatase ... #Algorithm #Hepatology ... #Differential #Diagnosis
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... hepatocellular pattern of liver ... upper limit of normal ... , AIH diagnosis ... #Hepatology