11 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... #Coagulation #Abnormal ... #APTT #Laboratory ... #Hematology #Diagnosis
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation ... (DIC) Platelet ... small vessels #DIC ... ISTH #Scoring #diagnosis ... #hematology #laboratory
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
venipuncture sites Laboratory ... • Severe Liver ... - APTT < 1.5 x normal ... #diagnosis #causes ... treatment #management #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
- Differential Diagnosis ... Algorithm Thrombocytopenia ... Destruction • Abnormal ... Iatrogenic) • Liver ... #Hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
MAHA: TTP, HUS, DIC ... Defects, Drugs, Liver ... Hypophostphatemia Laboratory ... Blood Smear ↑ abnormal ... #hematology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... Findings in Hepatic / Liver ... As a result of DIC ... LiverFailure #Hepatic #Hepatology ... #Laboratory #Diagnosis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... inhibitor of a coagulation ... Warfarin • Acute DIC ... disease • Acute DIC ... #Hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... (DIC) c. ... Prolonged #Causes #diagnosis
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... intravascularcoagulation (DIC ... amyloidosis #Abnormal ... #coagulation
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... the diagnosis and ... <45% and SF is normal ... #diagnosis #management ... #hepatology #gastroenterology