43 results
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Vasculitis -> Acute ... Pancreatitis - Elevated Liver ... - Budd Chiari Syndrome ... #signs #symptoms ... #diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics ... #neurology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... marrow) -dys- (abnormal ... transformation to acute ... #Management #treatment ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... - ACS, AKI, acute ... WBC >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... and Differential Diagnosis ... investigations abnormal ... clinical context and signs ... • Cardio-renal syndrome
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Multiple Sclerosis Treatment ... symptoms) • Acute ... #management #neurology ... #treatment #MS
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Renal Failure Treatment ... 500 mg QD until normal
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... lumbar spine Signs ... #MSK #pathophysiology ... #diagnosis #symptoms ... #signs
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Diagnostic Framework ... some patients) Normal ... kidney disease, Acute ... : Alcohol use, Liver ... Myelodysplastic syndrome