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hematology differential management oncology causes mds myelodysplastic activation afib aflp algorithm anticoagulation aplastic bleed chads2 chads2vasc common cvid disease elevatedmcv
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Myelodysplastic Syndromes ... Liver Function ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... marrow) -dys- (abnormal ... cytopenias (usually anemia ... #Management #treatment ... #hematology #oncology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... some patients) Normal ... : Alcohol use, Liver ... Myelodysplastic syndrome ... #causes #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... Defects: Sickle cell anemia ... Blood Smear ↑ abnormal ... #hematology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
deficiency - Anemia ... leads to chronic anemia ... the hepatorenal syndrome ... LiverFailure #Hepatic #Hepatology ... #Laboratory #Diagnosis
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation C Congestive Heart Failure 1 H Hypertension 1 A2 Age >75 2 D Diabetes Mellitus 1 S2 Stroke,
hypertension 1 A Abnormal ... Bleeding history/anemia ... CHADS2VASc #HASBLED #Comparison ... Anticoagulation #AFib #Diagnosis ... #Hematology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Hepatic imaging: Normal ... necrosis HELLP Syndrome ... Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... #differential #diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... (MDS) (normal or ... Treatment: ... #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... low and appear abnormal ... marrow studies Treatment ... Immunosuppressive treatment ... #diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
with leukopenia, anemia ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
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