6416 results
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm
Cervical:
 - Anterior
     • Infection
- Differential Diagnosis ... • Cancer (In absence ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
screening (in absence ... Hypercoagulable #Workup #hematology ... #diagnosis #algorithm ... #hematology #VTE
Complement Deficiency Testing Algorithm
 • Normal CH50 and AH50 AND High suspicion for complement deficiency
 •
deficiency • Low or absent ... AH50 • Low or absent ... Normal CH50 Low or absent ... Testing #Algorithm #hematology ... #diagnosis
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... IgD or IgE) • Absence ... immunofixation • Absence ... #Significance #hematology ... #diagnosis #oncology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
(CD41/CD61) is absent ... lX/V (CD42b) is absent ... Platelet #disorders #hematology ... #differential #diagnosis
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
deficiency) • Absence ... #differential #diagnosis ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Presentation / Diagnosis ... Diagnosis via genetic ... Splenomegaly • Low or absent ... Infection should be diagnosed ... management #treatment #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... - 5% RS cells absent ... pathophysiology #Hematology ... #Diagnosis #NonHodgkin
Von Willebrand Disease Classification
Type 1 (Accounts for ~3/4 of cases):
 • Defect: Quantitative defect (i.e. not
or near total absence ... Classification #Types #diagnosis ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Diagnostic Criteria - 2004 vs 2009

At least three of the following: 
 -
Lymphohistiocytosis (HLH) Diagnostic ... biopsy - Low/absent ... Lymphohistiocytosis #Diagnosis ... #Criteria #Hematology