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diagnosis clinical dermatology differential algorithm management rheumatology hepatology photo causes physicalexam skinrash video ucsdh treatment skin rash syndrome pathophysiology comparison
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
screening (in absence ... Hypercoagulable #Workup #hematology ... diagnosis #algorithm #hematology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
• Cancer (In absence ... Algorithm #Causes #Hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... sub-types based on the hematologic ... IgD or IgE) • Absence ... immunofixation • Absence ... #Significance #hematology
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
deficiency • Low or absent ... AH50 • Low or absent ... Normal CH50 Low or absent ... Testing #Algorithm #hematology
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
(CD41/CD61) is absent ... lX/V (CD42b) is absent ... Platelet #disorders #hematology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
deficiency) • Absence ... differential #diagnosis #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- 5% RS cells absent ... pathophysiology #Hematology
Von Willebrand Disease Classification Type 1 (Accounts for ~3/4 of cases): • Defect: Quantitative defect (i.e. not
or near total absence ... Types #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Splenomegaly • Low or absent ... management #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Diagnostic Criteria - 2004 vs 2009 At least three of the following: -
biopsy - Low/absent ... Diagnosis #Criteria #Hematology
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