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ana patterns testing antibodies cytoplasmic nuclear anca antineutrophil arthritis bleeding bruising causes classification disease diseases erythematosus hematology imdamnsharp laboratory lupus
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
SHARP - Lupus Diagnosis ... Discoid Rash A Antinuclear ... Antibody (ANA) ... IMDAMNSHARP #sle #systemic ... erythematosus #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... antibodies) • Systemic ... #Antinuclear #Antibody ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Kumfer @AnnKumfer #Antinuclear ... #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers ... Kumfer @AnnKumfer #Antinuclear ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... • Reticular/AMA ... #Antinuclear #Antibody ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... PBC/SjS OS • AMA ... #Antinuclear #Antibody ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Diagnosis Algorithm ... ASA) • Renal Disease ... Vascular System ... #Diagnosis #Algorithm ... #Causes #Hematology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... ARUPConsult @ARUPLabs #ANA ... #Antinuclear #Antibody ... Nuclear #Patterns #differential ... #diagnosis #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... erythematosus (SLE) - Antinuclear ... antibody (ANA) ... #testing #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
< 30 years - Aorta ... branches • GCA: - Aorta ... Diagnosis: Systemic ... LFT • ESR • ANA ... #diagnosis #rheumatology
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