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diagnosis differential video physicalexam rheumatology management ophthalmology causes nephrology lupus symptoms algorithm signs systemic treatment workup ocular dermatology pathophysiology syndromes
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Discoid lupus erythematosus ... : Lupus erythematosus ... , Loose anagen syndrome ... • Signs of any ... DHEAS) • ANA
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... alopecia Differential ... Clinical Features ... • Nonscarring alopecia
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Photosensitivity, Alopecia ... Workup: - ANA ... lupus #Systemic #Erythematosus
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... (SLE), Sjogren's ... Syndrome (SS), ... (SLE), Systemic ... Antinuclear #Antibodies #ANA
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
General (Diffuse and ... required • Lupus erythematosus ... • Loose anagen syndrome ... totalis (all scalp and ... Discoid lupus erythematosus
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Clinical and Immunologic ... - NON-SCARRING ALOPECIA ... SEROSITIS - RENAL - NEUROLOGIC ... IMMUNOLOGIC CRITERIA - ANA
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Systemic #Lupus #Erythematosus
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... (SLE) Clinical ... Demyelinating Syndrome ... Systemic #Lupus #Erythematosus ... #SLE #CNS #neurology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Clinical Domains ... : Non-scarring alopecia ... least 2 joints • Neurologic ... low C4, Low C3 and ... Classification #Criteria #SLE
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... causes: • Susac syndrome ... • Sjögren syndrome ... Systemic lupus erythematosus ... #neurology #inflammatory
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