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diagnosis rheumatology management erythematosus differential signs bee criteria hematology syndromes activation algorithm ana anisocoria antibodies antinuclear behcet cerebritis chronic classification
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Photosensitivity, Alopecia ... life-threatening • Treatment ... #lupus #Systemic
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
conjunction with symptoms ... central nervous system ... diagnosis and treatment ... • Systemic lupus ... #neurology #inflammatory
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... (SLE) Clinical ... Demyelinating Syndrome ... Puncture, EEG Treatment ... #SLE #CNS #neurology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... • Treatment: ... months to years) Systemic ... Photosensitivity, Alopecia
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic ... Criteria CLINICAL ... - NON-SCARRING ALOPECIA ... SEROSITIS - RENAL - NEUROLOGIC
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Clinical Domains ... : Non-scarring alopecia ... least 2 joints • Neurologic ... Classification #Criteria #SLE ... #Systemic #Lupus
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... Demyelinating syndromes ... #SLE #systemic ... erythematosus #signs #symptoms
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... Syndrome (SS), ... (SLE), Systemic ... (SLE), Systemic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... and permanent alopecia ... : • Symptoms limited ... #Systemic #Lupus
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
develops on the background ... lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... Treatment: • Corticosteroids
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