892 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Features: POEMS, AL amyloid ... • Organized Ig deposits ... : Ig-related amyloid ... Non-organized Ig deposits ... monoclonal Ig deposits
Nephrotic Syndrome - Classification
 - Podocytopathies
 - Immunocomplex Deposits 
 - Other substances Deposits 

#Nephrotic #Syndrome
Immunocomplex Deposits ... Other substances Deposits
Great Mimickers - SHALLOTS Mnemonic

S- Syphilis - Neurosyphilis, aortitis, gummas... Granulomas can form anywhere! Skin, mucosa,
A - Amyloid - Amyloid ... deposits everywhere
This image shows spicular amyloid deposits showing blunt conical formations with interconnecting fibrils.

Dr. Stephen Bonsib via
shows spicular amyloid ... deposits showing ... arkanalabs #amyloid ... #deposits #deposition
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Amyloidosis: • Primary amyloid ... dyscrasias • Secondary amyloid ... Bone/Joint: • Amyloid ... (AMYLOID ANGIOPATHY ... Protein • AL Amyloid
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
glomerulopathy (Dense deposit ... Minimal immune deposits
This image shows portions of glomerular tuft with collapsed GBM (across top), spicular amyloid (middle right),
top), spicular amyloid ... ), and nodular amyloid ... glomerulus #GBM #amyloid ... #desposition #deposits
Cutaneous Manifestations of Monoclonal Gammopathy
 • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Extravascular lg Deposits ... Intravascular lg deposits
This image shows spicular amyloid with tapering conical masses interconnected by branching fibrils!

Dr. Stephen Bonsib via
shows spicular amyloid ... arkanalabs #amyloid ... #desposition #deposits
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
Presence of immune deposits ... on IF • No EM deposits ... Minimal immune deposits