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diagnosis hepatology algorithm acute treatment aki cirrhosis druginduced gastroenterology aclf albumin causes chemistry chronic criticalcare diuresis diuretics drug drugs endocrinology
Drugs and Classes Associated with DILI and Type of Liver Injury #Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... and Type of Liver ... Injury #Medications ... #Differential # ... LiverInjury #Hepatology #Pharmacology
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 Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Injury (DILI) ... dose dependent injury ... #differential # ... Diagnosis #Management
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Skin involvement, Kidney ... injury, Previous ... duration), Several medications ... #Injury #Diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... • Iatrogenic: DILI ... cardiac muscle, kidneys ... #differential #
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... Circulation Failure Kidney ... Injury (DILI) ... Hepatitis Procedures Management ... gastroenterology #management
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
cardiac muscle, RBC, Kidney ... Cardiac muscle, Kidneys ... trimester placenta, kidneys ... Unconjugated Bili ... chemistry #diagnosis #differential
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
Medications causing ... Acute Kidney Injury ... #Injury #Medications ... #Drugs #pharmacology ... #differential #
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
Indications for ... Albumin for Management ... removed • Acute kidney ... injury (≥ 1B) - ... #Management #Cirrhosis
Acute Kidney Injury (AKI) - Management Principles Prerenal - Correct hemodynamic derangements: • If low preload →
Acute Kidney Injury ... (AKI) - Management ... Treat underlying liver ... #Injury #treatment ... #management
Hypocalcemia - Diagnosis and Management PTH Independent (↑ PTH) • LOW VIT D -
Diagnosis and Management ... - Activation: Liver ... disease, Kidney ... Transfusions - Medications ... endocrinology #differential
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