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diagnosis sle erythematosus systemic druginduced hematology comparison summary treatment vasculitis algorithm ana anemia antibodies antibody antinuclear autoantibodies autoimmune bleeding bone
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Diagnosis Manifestations ... (aPL) 30-45% Differential ... Diagnosis and Lupus ... symptoms #mimickers #differential ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... and Management ... Erythematosus #Diagnosis ... #rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
, Gemcitabine Lupus ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential ... #diagnosis #comparison ... #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... #Systemic #Lupus ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Drug Induced Lupus ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... Limited to Kidney: Anti-GBM ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Hemolytic Anemia 1) DIAGNOSE ... bilirubin, ↑ LDH • Anti-RBC ... • Blood smear: Differential ... #management #treatment ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Non-autoimmune rheumatologic ... Erythematosus #Diagnosis ... #Rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antibodies (ANA) ANA or Anti-NucIear ... , Drug-induced Lupus ... , Drug-Induced Lupus ... ANA #patterns #rheumatology ... #diagnosis #differential
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Can present from infancy ... predispose to other orthopedic ... • Differentiate ... #diagnosis #causes ... #hematology
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