43 results
diagnosis causes systemic erythematosus hematology sle classification management ana antibodies antinuclear autoantibodies dermatology pulmonary table diseases renal syndromes thrombocytopenia associations
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... Vasculitis: • ... Renal-limited vasculitis ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... ANA (anti-nuclear ... Vasculitis: P-ANCA ... #diagnosis #associations
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
c-ANCA - Vasculitis ... granulomatosis p-ANCA ... - Vasculitis, e.g ... #diagnosis #table ... #rheumatology #
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... Diagnosis for Pulmonary ... Complex: Systemic lupus ... testing: anti-ANCA ... , ANA, C3, C4, anti-CCP
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... Disease (Goodpasture's ... #differential # ... diagnosis #algorithm ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
(anti-C1q Vasculitis ... such as systemic lupus ... testes -> pain, infarct ... differential #diagnosis ... #rheumatology #
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
ANCA-Associated ... 90%, rarely PR3 Anti-GBM ... disease - MPO>PR3 ... MPO #PR3 #Diagnosis ... #Rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Auto-Antibodies: - ANA ... (aPL) 30-45% Differential ... Diagnosis and Lupus ... sclerosis, Still's disease ... #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
small vessels - ANCA-associated ... - systemic lupus ... #Vessels #Diagnosis ... #Rheumatology # ... Diagnosis
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
M DAMN SHARP - Lupus ... Diagnosis Mnemonic ... Antinuclear Antibody (ANA ... Arthritis R Renal Disease ... erythematosus #rheumatology
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