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diagnosis erythematosus hematology causes joint systemic algorithm dermatology disease signs symptoms ana antibodies antinuclear autoantibodies bruising management skin thrombocytopenia agglutinin
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... glycoprotein I (ß2GP), Lupus ... Polymerase Ill • ANCA Vasculitis ... #diagnosis #associations
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
involvement 3% SLE-Related ... (aPL) 30-45% Differential ... Diagnosis and Lupus ... Lupusreference #SLE ... #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint Pain ... lesions • Discoid lupus ... dermatology #joint #pain ... #skin #rashes #differential ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Arthritis: • Joint pain ... #Rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... drug-induced SLE ... ANCA-Associated Vasculitis ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Diagnosis Framework ... Secondary: CTD: SLE ... Ig A (HSP) - Anti-C1q ... #dermatology #rheumatology ... diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
(anti-C1q Vasculitis ... , infarct • Small ... , and SLE) • Urinalysis ... differential #diagnosis ... #rheumatology #
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Diagnosis Framework ... (RA), Systemic lupus ... erythematosus (SLE ... #Diagnosis #rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Rheumatica • Pain ... , Gemcitabine Lupus ... Myopathies #myopathy #differential ... #diagnosis #comparison ... #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... Glomerulonephritis #Vasculitis ... #differential # ... diagnosis #algorithm ... #rheumatology
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