2553 results
25 yo Honduran female w viral infx gets IV bolus & goes into pulm edema; POC
Doming of ant mitral ... Rheumatic Heart Disease ... @NagdevArun #Clinical ... #POCUS #Echocardiogram
43 yo M w L ant neck swelling, pain, fever x 2 d. Got the Dx?

...

Infectious
43 yo M w L ant ... DavidPigottMD #Clinical ... #POCUS #Neck #SCM ... Lemierres #Syndrome #Disease
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and their Disease ... - Graves' disease ... connective tissue disease ... (TTG) - Celiac disease ... #Associations #diseases
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Anti-dsDNA (in 70% ... Anti-histone (in ... connective tissue disease ... disease - MPO>PR3 ... #rheumatology #diseases
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
60-70% - Anti-SSA ... 5-10% - Anti- ... 5-15% - Anti-Ku ... auto-immune, Infectious diseases ... sclerosis, Still's disease
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Autoantibodies Anti-topoisomerase ... I (anti-Sc170): ... Diffuse skin disease ... : Limited skin disease ... Biliary Cirrhosis Anti-RNA
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
screening test Anti-dsDNA ... with more severe disease ... activity Anti-Ro ... Sjogren syndrome Anti-UI-ribonucleoprotein ... overlap syndrome) Anti-Smith
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Systemic lupus Anti-dsDNA ... Association with disease ... Anti-histone 60 ... -15% If SLE is clinically ... with auto-immune diseases
Male Sexual and Erectile Dysfunction - Differential Diagnosis Algorithm
Erectile Dysfunction
 - Psychological
    •
Sensate • Focus ... • Anti-depressants ... Amphetamines) Chronic Disease ... Cardiovascular Disease ... Connective Tissue Disease
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
vasculitis, Behcet disease ... Goodpasture's Disease ... testing: anti-ANCA ... ab, anti-GBM ab ... , ANA, C3, C4, anti-CCP