17 results
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... delayed HTR • Drug-induced ... • PNH • Drug-induced ... #Differential #Diagnosis ... #Hematology
Medications associated with drug-induced lupus

List of Definite and Possible Associated Drugs

#Diagnosis #Pharmacology #Medications #DrugInduced #Lupus #List
with drug-induced ... Possible Associated Drugs ... #Diagnosis #Pharmacology ... #Lupus #List #Causes ... Drugs
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... usually IgG) (e.g. lupus ... infection) - Drugs ... #Causes #differential ... #diagnosis #hematology
Drug-Induced Thrombocytopenia
The diagnosis of drug-induced thrombocytopenia can be made only by demonstrating resolution of thrombocytopenia once
Drug-Induced Thrombocytopenia ... drug-induced thrombocytopenia ... once a suspected drug ... patients with drug-induced ... #Diagnosis #Hematology
Drug-Induced Seizures - OTIS-CAMPBELL

O - Organophosphate, oral hypoglycemics, opioid
T - TCA, theophylline
I - Isoniazid, Insulin
S -
Drug-Induced Seizures ... Kat_Watson #Drug ... #Medication #Causes ... #Differential # ... Pharmacology #Diagnosis
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Diagnosis Algorithm ... Destruction • Abnormal ... Congenital - Rare • Drugs ... #Causes #Hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... AIHA: warm, cold, drug ... induced • Infections ... #Diagnosis #causes ... classification #hematology
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Drug Induced Systemic ... > 100 drugs have ... associated with drug-induced ... #drugs #pharmacology ... #diagnosis #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... cases, drug-dependent ... - Less common (drug-dependent ... drug +++, Hydroxychloroquine
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Drugs: Direct or ... indirect inhibitory drugs ... #diagnosis #differential ... #hematology #coagulation