42 results
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
ANA level above laboratory ... - Anti-dsDNA antibody ... level above laboratory ... the presence of antibody ... #Diagnosis #Rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ... (anti-nuclear antibody ... Antiphospholipid Antibody ... LAC) • Sjogren Syndrome ... #associations #table
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Wiskott-Aldrich syndrome ... Diseases: • Systemic lupus ... hemoglobinuria • Antibody-mediated ... Differential #Diagnosis #Hematology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
BEE Syndromes - ... Inflammatory causes ... : • Susac syndrome ... encephalomyelitis • MOG antibody-associated ... • Systemic lupus
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear Antibody ... ) • Systemic lupus ... anti-topoisomerase antibody ... • Sjögren syndrome ... antibodies #diagnosis #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
calcium-b) • Laboratory ... Discontinuation of causal ... versus DIL • Laboratory ... sle #comparison #table ... #rheumatology #
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
La) - Sjogren's syndrome ... polyangiitis U1-RNP antibody ... disease Endomyseal antibody ... diseases #diagnosis #table ... #rheumatology #
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Antiphospholipid-antibody ... syndrome • Vasculitis ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... versus DIL • Laboratory ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Principal Causes of Generalized Edema - History, Physical Examination, and Laboratory Findings 

Cardiac, Hepatic, Renal (ARF),
Principal Causes ... Examination, and Laboratory ... Renal (Nephrotic Syndrome ... #Differential #Table