39 results
Marfan Syndrome - Signs and Symptoms

- Caused by mutations in the fibrillin-1 (FBN1) Gene (chromosome 15)
-
Marfan Syndrome ... - Signs and Symptoms ... - Caused by ... chromosome 15) - Abnormal ... #Diagnosis #Signs
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Manifestations of Serotonin Syndrome ... • Ophthalmologic ... Dermatologic: Diaphresis, flushing ... Cardiovascular and vital sign ... Symptoms #spectrum #signs
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Extra-renal Losses: • Normal ... Carbenoxolone, SAME, Cushing ... Syndrome • HTN ... , Gitelman syndrom ... Diagnosis #Algorithm #causes
Adie's Pupil
What? Unknown nature & benign
 • Regular and mildly dilated pupil (4-6mm);
 • Light-near dissociaton;
reexposed to light; • Normal ... Holmes-Adie Syndrome ... Ill Palsy - abnormal ... dissociation • Other causes ... PhysicalExam #neurology #ophthalmology
Abnormalities in Rate and Rhythm of Breathing 
Normal 
The respiratory rate is about 14—20 per min
Sighing Respiration ... punctuated by frequent sighs ... hyperventilation syndrome—a ... Occasional sighs ... Abnormalities #Abnormal
Differential diagnoses for the neuro-ophthalmologic finding of diplopia.
Neoplastic: 
 • Intraorbital meningioma 
 • Pituitary adenoma
for the neuro-ophthalmologic ... finding of diplopia ... Miller-Fisher syndrome ... Differential #Diagnosis #Causes ... #Ophthalmology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer's (99% of cases ... mutations - Down syndrome ... chromosome 21) Signs ... Aphasia, word-finding ... geriatrics #diagnosis #signs
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
osmolarity If cause ... investigations abnormal ... clinical context and signs ... Abdominal compartment syndrome ... • Cardio-renal syndrome
Pulmonary Pathology and Associated Lung Ultrasound Findings
Pneumothorax:
 - No lung sliding/barcode sign
 - Lung point (hard
sliding/barcode sign ... Consolidations - "Shred" sign ... pleura in severe cases ... Respiratory Distress Syndrome ... differential #diagnosis #signs
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
incidental CXR finding ... ), liver (pain/abnormal ... Specific sarcoidosis syndromes ... • Heerfordt syndrome ... Diagnosis #Management #Signs