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diagnosis hematology algorithm classification hemolysis workup autoimmune deficiency extravascular fever intravascular management nutrition purpura rheumatology table abnormal agglutinin aiha antibody
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... Transfusion reaction, Paroxysmal ... Extravascular #Causes ... #differential #
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... #Hemolytic #Anemia ... #Algorithm #Differential ... #Causes #Workup
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - ... Differential Diagnosis ... Donath-Landsteiner HA (paroxysmal ... #Anemia #AIHA #
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... incompatibility • Paroxysmal ... udaygulati #Hemolytic ... #Anemia #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... - Differential ... → Sickle Cell anemia ... #Anemia #Differential ... Diagnosis #Algorithm #causes
Causes of Hemolytic Anemia - Differential Diagnosis Inherited • Membrane • Internal - Hemoglobin
Causes of Hemolytic ... Anemia - Differential ... Sophia_Hayes_MD #Hemolytic ... #Anemia #Differential ... #Diagnosis #Causes
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Antibody Autoimmune Hemolytic ... Anemia 1) DIAGNOSE ... AIHA • Anemia ... • Blood smear: Differential ... 2) LOOK FOR a cause
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Volume (MCV) - Differential ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... #Differential #
Anemia - Workup and Differential Diagnosis - History, Physical Exam, Labs - Microcytic - Normocytic -
Anemia - Workup ... and Differential ... Macrocytic - Hemolytic ... #Differential # ... Diagnosis #causes
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential ... anemia • ... Extravascular #Differential ... Diagnosis #Algorithm #Causes
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