21 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... Allogeneic stem cell ... #Management #treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... aplasia • ITP ... microglobulin Treatment ... #workup #oncology ... #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Consider stem cell ... if neutropenic fever ... #Anemia #diagnosis ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
- Differential Diagnosis ... Megakaryopoiesis • Aplastic ... ITP • SLE • CLL ... Non-lmmune: • HELLP Syndrome ... #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Lymphadenopathy • HSM • Fevers ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... ) B symptoms → fevers ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... • Induce blast cell ... Subacute-Acute: • Common: fever ... #oncology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
general feeling of ill ... Leukemia cutis Diagnosis ... Treatment: - Systemic ... #diagnosis #dermatology ... #oncology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
) Differential Diagnosis ... Algorithm DIFFUSE ... • Loose anagen syndrome ... Follicularis • Aplasia ... HairLoss #Alopecia #dermatology