28 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Disease, PRES Pathophysiology ... #rheumatology # ... cerebritis #diagnosis #management ... #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... - CRP: Usually normal ... life-threatening • Treatment ... #Systemic #Erythematosus ... #Summary #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... #Lupus #Erythematosus ... Summary #diagnosis #rheumatology ... #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... months to years) Systemic ... life-threatening • Treatment ... Usual therapeutic management ... #diagnosis #management
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... #treatment #management ... #rheumatology # ... nephrology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... lupus erythematosus ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the Treatment ... of Membranous Lupus ... proteinuria (<3.5g/d, normal ... #Membranous #Lupus ... #management #nephrology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
solid cancers • Systemic ... • Muscular: normal ... CK, normal biopsy ... Disease #diagnosis #management ... #treatment #rheumatology
Holistic Management of Systemic Lupus
 • Lifestyle interventions: Smoking cessation, Photoprotection, Therapeutic adherence, Anxiety/depression/fatigue, Fibromyagia/pain management,
of Systemic Lupus ... holistic #SLE #Systemic ... #Lupus #Erythematosus ... #management #treatment ... #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
50 in GCA, but normal ... of the steroid treatment ... Treatment of GCA ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management