24 results
Prehension / Adult Palmar Grasp Reflex (Abnormal)
Notice friends that the patient always "tries to grab" my
Prehension / Adult ... (Abnormal) Notice ... like something "normal ... #Adult #Neurology ... clinical #video #abnormal
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... etiology of coma Abnormal ... movements; also normal ... flexion withdrawal, abnormal ... decortication), abnormal
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview Normal ... Segmented Neutrophil (Normal ... Chemotherapy Even with normal ... shock, 33% had normal ... #pathophysiology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Microangiopathy (TMA) - Differential ... Diagnosis and Management ... hemosiderin • PT/aPTT normal ... #Diagnosis #Management ... #Algorithm #hematology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Idiopathic • Normal ... Glomerulonephritis #Vasculitis #differential ... diagnosis #algorithm #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... • Muscular: normal ... CK, normal biopsy ... Disease #diagnosis #management ... #treatment #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... 500 mg QD until normal ... APML #diagnosis #management ... #hematology #oncology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... Decreased / Absent Reflexes ... CSF PROTEIN - NORMAL ... Syndrome #diagnosis #management ... #treatment #neurology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Thrombocytopenia - Normal ... - APTT < 1.5 x normal ... causes #treatment #management ... #hematology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... injury • Gait is abnormal ... dysfunction • Abnormal ... reflexes: Areflexia ... disorders #diagnosis #neurology