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diagnosis rheumatology differential algorithm management sle erythematosus causes dermatology classification druginduced hemeonc nephrology oncology treatment vasculitis activation antiphospholipid autoimmune cerebritis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... • Immunologic Workup ... Positive in 60-80% of cases
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Autoimmune Vasculitis (lupus ... : - ITP - APLS ... deficiency Work ... #Causes #dermatology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
Vesiculobullous Skin Rash ... Differential Diagnosis Algorithm ... • Bullous systemic ... lupus erythematous ... #causes
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... Thrombocytopenia #Lupus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Clinical Features ... Antiribosomal P, APLA ... disorders • CAD APLA
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... (for secondary APS
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... • Immunologic Workup ... months to years) Systemic ... • Immunologic Workup
Mucous Membrane Disorder - Differential Diagnosis Algorithm Erosions/Ulcers/Blisters - Primary Dermatologic Diseases •
Differential Diagnosis Algorithm ... Stevens-Johnson Syndrome ... necrolysis - Systemic ... lupus erythematosus ... #causes
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... Clinical Presentation ... Fever is the main clinical ... Petechial or purpuric rash ... lupus erythematosus
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... 6) An annular rash ... search ANA and aPL ... #system #erythematosus ... #rheumatology
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