16 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... and risk-stratification ... • Risks: infection ... transformation to acute ... #hematology #oncology
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Algorithmic Approach ... to Acute Interstitial ... triad (<10%): fever ... MatthewHoMD #Acute ... #diagnosis
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential Diagnosis ... death Neutropenic Fever ... cells/mm3 • Single ... Hyperuricemia • Acute ... #differential #diagnosis
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... fever without source ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... Stratification #Fever
Causes of Sudden Unexpected Death in Infancy (SUDI) - Differential Diagnosis Algorithm
Congenital Anomaly / Disorder:
 •
Unexpected Death in ... Accidental* Other: • Acute ... 80% of SUDI • Risk ... #Algorithm #Causes ... #Peds #Pediatrics
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Attempt if high risk ... : • Common: fever ... Renal Failure Treatment ... management #hematology #oncology
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
LBRF can be diagnosed ... of blood smear, acute ... a single dose! ... often experience acute ... initiation of treatment
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... : - Fever + ANC ... mg/dL or > 25 % rise ... Treat underlying cause ... #HemeOnc #Diagnosis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome Acute ... Causes: - Idiopathic ... Treatment: - Systemic ... Sweet #Syndrome #diagnosis ... #dermatology #oncology
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Trypanosomiasis - Diagnosis ... infectious disease caused ... weeks incubation Acute ... mild (malaise, fever ... Tests - check Acute