10 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... incontinence, apraxia ... AlzheimersDisease #Dementia ... #pathophysiology
Causes of Hemiplegia - Differential Diagnosis Algorithm
Cerebral Hemisphere (Contralateral motor cortex)
 • Aphasia
 • Apraxia
 •
Causes of Hemiplegia ... • Aphasia • Apraxia ... Cognition/Confusion, Dementia ... Brown-Sequard Syndrome ... #Hemiplegia #Neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... Other brainstem syndromes ... facial numbness), Encephalopathy ... Manifestations #diagnosis #neurology ... #symptoms #signs
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Meningitis, Myelopathy, Encephalopathy ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Pathophysiology ... Classic HIV Encephalopathy ... The clinical syndrome ... dysfunction like gait ... #AIDS #Neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Posterior Reversible Encephalopathy ... may precede the neurologic ... Etiology: • Pathophysiology ... the underlying cause ... #management #neurology
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
soles in 50% of cases ... and nephrotic syndrome ... have positive serology ... tabes dorsalis, gait ... impairments, and dementia
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Stiff Person Syndrome ... Prevalence: 1-2 cases ... Pathophysiology ... • Wide based gait ... Management #treatment #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
• Symptoms and signs ... of injury • Gait ... Non-compressive Spinal Cord Causes ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
• Locked-in syndrome ... • Mutism Pathophysiology ... • Examine for signs ... Casey Albin MD @ ... #PhysicalExam #neurology