18 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Fever is the main clinical ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Seizure disorders, Aseptic ... Puncture, EEG Treatment ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... sequestration and activation ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... excessive macrophage activation ... • Bicytopenia Treatment ... diagnosis #management #treatment ... #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS) - Differential ... Diagnosis Neurologic-Centered ... Monoclonal #Gammopathy #Clinical ... #Diagnosis #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... initiation • Differential ... Diagnosis: Infection (sepsis ... Renal Failure Treatment ... diagnosis #management #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
complex → plt activation ... Diagnosis: • Clinical ... non-heparin A/C if clinical ... Diagnosis #Management #Treatment ... #Hematology #HemeOnc
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
history of trauma, sepsis ... organ damage Clinical ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Treatment depends ... anaesthesia • Sepsis ... Phaeochromocytoma Neurologic ... #Hyperthermia #Differential
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Eclampsia, Infection/Sepsis ... Reversible course Differential ... epilepticus Treatment ... underlying cause • Treatment