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diagnosis hematology bleeding purpura acronym algorithm anemia arterial blanching bruise coagulation comparison criticalcare dic disseminated ecchymosis embolism extravascular framework hematomas
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm Thrombocytopenia ... • Disseminated Intravascular ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... - Disseminated intravascular ... microangiopathy: Thrombotic thrombocytopenic ... #Causes #differential ... #diagnosis #hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... or Easy Bruising ... (disseminated intravascular ... #Causes #peds # ... pediatrics #diagnosis #differential
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... - Bacterial: Sepsis ... #Differential # ... Diagnosis #Framework #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... history of trauma, sepsis ... Treat primary cause ... #Disseminated #Intravascular ... Coagulation #diagnosis #causes
Shock - Differential Diagnosis Framework MAP = CO x SVR Hypovolemic (↓ Intravascular volume): • Hemorrhage, dehydration due
Shock - Differential ... Hypovolemic (↓ Intravascular ... findings based on cause ... Vascular tone): • Sepsis ... #Diagnosis #table
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Arterial Thrombosis - Differential ... Heparin-induced thrombocytopenia ... - Disseminated intravascular ... coagulation and other causes ... #differential #
PLATELETS Mnemonic for Causes of Thrombocytopenia P - Platelet Disorders (DIC, ITP, TTP) L - Leukemia, Lymphoma A -
PLATELETS Mnemonic for Causes ... of Thrombocytopenia ... Heparin-induced) S - Sepsis ... #Differential # ... Diagnosis #Hematology
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
individuals with thrombocytopenia ... ecchymosis) is caused ... of blood in the extravascular ... Excessive bruising ... VWF:RCo/VWF:Ag (differentiate
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... decrease in most cases ... reflection of intravascular ... WBC count and differential ... Diagnosis #Workup #Hematology
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