12 results
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... child * Severe cases ... @Bloodman #Thrombocytopenia ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... child * Severe cases ... #Thrombocytopenia ... AFLP #obstetrics #hematology ... #diagnosis #table
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... - Bacterial: Sepsis ... antiphospholipid syndrome - Pregnancy ... #Differential #
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... • Wilson's • Pregnancy ... Drugs • TPN • Sepsis ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... hypersplenism and related thrombocytopenia ... Fatty liver of pregnancy ... #Diagnosis #causes ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Toxic: Medication, Pregnancy ... • Infectious: Sepsis ... Acute #algorithm #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
history of trauma, sepsis ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... Intravenous Drug Use • Pregnancy ... Heparin-induced thrombocytopenia ... coagulation and other causes ... #differential #
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... = nonspecific (nausea ... infiltration) Differential ... #Fatty #Liver #Pregnancy ... #hepatology #obstetrics
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Differential Diagnosis ... Management during ... Management during ... Delivery • Stable