20 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... syndrome (ST-HUS ... known as atypical HUS ... #schistocytes #differential ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Intravascular Hemolysis ... - Differential ... MAHA (TTP, DIC, HUS ... Extravascular #Differential ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Intravascular Hemolysis ... uremic syndrome (HUS ... Extravascular #Causes #differential ... #diagnosis #hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy (TMA) - Differential ... Diagnosis Table ... HUS (aHUS) ... Microangiopathy #TMA #hematology ... #differential #
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - Differential ... Diagnosis Table ... #Diagnosis #Table ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... DIC, TTP, HELLP, HUS ... #Anemia #Differential ... Algorithm #workup #hematology
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Production • Hemolysis ... Hepatic Uptake • Sepsis ... Post-Hepatic - Usually has ... Algorithm #Causes #Hepatology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Microangiopathy - TTP VS HUS ... Often hard to differentiate ... HemolyticUremicSyndrome #HUS ... Comparison #Diagnosis #Table ... #Hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
TTP/HUS indicates ... thrombocytopenic purpura/hemolytic ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... - MAHA: TTP, HUS ... Urobilinogen #Hemolysis ... #Differential # ... Diagnosis #hematology